Prime Medicine Net Debt Growth & History (PRME)
Prime Medicine's net debt was $53.4M for fiscal 2025.
View full Prime Medicine company overviewPrime Medicine annual net debt history
| Fiscal year | Period ended | Net debt | Change | Growth |
|---|---|---|---|---|
| 2025 | 2025-12-31 | $53.4M | $195.1M | — |
| 2024 | 2024-12-31 | −$141.7M | −$113.7M | — |
| 2023 | 2023-12-31 | −$27.9M | $130.9M | — |
| 2022 | 2022-12-31 | −$158.9M | $16.1M | — |
| 2021 | 2021-12-31 | −$175.0M | — | — |
Prime Medicine quarterly net debt
| Fiscal quarter | Period ended | Net debt | Change | YoY change |
|---|---|---|---|---|
| Q2 2026 | 2026-06-30 | $65.0M | −$905,000 | −1.37% |
| Q1 2026 | 2026-03-31 | $50.4M | $21.1M | +72.19% |
| Q4 2025 | 2025-12-31 | $53.4M | $195.1M | — |
| Q3 2025 | 2025-09-30 | $46.7M | $123.5M | — |
| Q2 2025 | 2025-06-30 | $65.9M | $79.9M | — |
| Q1 2025 | 2025-03-31 | $29.3M | $79.6M | — |
| Q4 2024 | 2024-12-31 | −$141.7M | −$113.7M | — |
| Q3 2024 | 2024-09-30 | −$76.7M | −$49.8M | — |
| Q2 2024 | 2024-06-30 | −$14.0M | $81.1M | — |
| Q1 2024 | 2024-03-31 | −$50.4M | $57.1M | — |
| Q4 2023 | 2023-12-31 | −$27.9M | $130.9M | — |
| Q3 2023 | 2023-09-30 | −$26.9M | −$10.4M | — |
| Q2 2023 | 2023-06-30 | −$95.1M | — | — |
| Q1 2023 | 2023-03-31 | −$107.5M | — | — |
| Q4 2022 | 2022-12-31 | −$158.9M | $16.1M | — |
| Q3 2022 | 2022-09-30 | −$16.5M | — | — |
| Q4 2021 | 2021-12-31 | −$175.0M | — | — |
Prime Medicine net debt trends
Between the periods ended 2021-12-31 and 2025-12-31, Prime Medicine's net debt increased from −$175.0M to $53.4M, a change of $228.4M. The latest reported quarter, Q2 2026, shows $65.0M.
What net debt means
Net debt compares a company’s interest-bearing debt with its cash and cash equivalents. Positive net debt means debt exceeds cash, while a negative value indicates the company has more cash than debt on this measure.
How net debt is calculated
TickerStat calculates net debt as total interest-bearing debt minus cash and cash equivalents at the same reporting-period end. Short-term investments are not subtracted because they are not included in the standardized cash series. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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