Prime Medicine Net Profit Margin Growth & History (PRME)
Prime Medicine's net profit margin was −4,342.44% for fiscal 2025.
View full Prime Medicine company overviewPrime Medicine annual net profit margin history
| Fiscal year | Period ended | Net profit margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −4,342.44% | +2224.17 pp |
| 2024 | 2024-12-31 | −6,566.61% | — |
| 2020 | 2020-12-31 | −65.45% | — |
Prime Medicine quarterly net profit margin
| Fiscal quarter | Period ended | Net profit margin | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | −3,648.96% | +1067.72 pp |
| Q1 2026 | 2026-03-31 | −5,738.55% | −2169.78 pp |
| Q4 2025 | 2025-12-31 | −5,498.69% | −3562.09 pp |
| Q3 2025 | 2025-09-30 | −4,129.14% | +20999.09 pp |
| Q2 2025 | 2025-06-30 | −4,716.68% | — |
| Q1 2025 | 2025-03-31 | −3,568.78% | +4174.20 pp |
| Q4 2024 | 2024-12-31 | −1,936.60% | — |
| Q3 2024 | 2024-09-30 | −25,128.23% | — |
| Q1 2024 | 2024-03-31 | −7,742.98% | — |
Prime Medicine net profit margin trends
Over the last five fiscal years, Prime Medicine's net profit margin decreased from −65.45% to −4,342.44%, a change of −4276.99 percentage points. The latest reported quarter, Q2 2026, shows −3,648.96%.
What net profit margin means
Net profit margin measures the percentage of revenue remaining as net income after operating costs, interest, taxes, and other expenses. It shows how much bottom-line profit or loss a company generates from each dollar of revenue.
How net profit margin is calculated
TickerStat calculates net profit margin as SEC-reported net income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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