Prime Medicine annual operating expenses
2020
2021
2022
2023
2024
2025
Prime Medicine Operating Expenses Growth & History (PRME)
Prime Medicine's operating expenses was $213.0M for fiscal 2025.
View full Prime Medicine company overviewPrime Medicine annual operating expenses history
| Fiscal year | Period ended | Operating expenses | Change | Growth |
|---|---|---|---|---|
| 2025 | 2025-12-31 | $213.0M | $7.5M | +3.67% |
| 2024 | 2024-12-31 | $205.4M | $658,000 | +0.32% |
| 2023 | 2023-12-31 | $204.8M | $88.2M | +75.72% |
| 2022 | 2022-12-31 | $116.5M | $32.1M | +37.96% |
| 2021 | 2021-12-31 | $84.5M | $78.3M | +1275.35% |
| 2020 | 2020-12-31 | $6.1M | — | — |
Prime Medicine quarterly operating expenses
Q3.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
Q1.26
Q2.26
| Fiscal quarter | Period ended | Operating expenses | Change | YoY change |
|---|---|---|---|---|
| Q2 2026 | 2026-06-30 | $44.4M | −$10.1M | −18.45% |
| Q1 2026 | 2026-03-31 | $51.5M | −$2.3M | −4.34% |
| Q4 2025 | 2025-12-31 | $49.4M | $3.0M | +6.55% |
| Q3 2025 | 2025-09-30 | $55.2M | $757,000 | +1.39% |
| Q2 2025 | 2025-06-30 | $54.5M | −$1.2M | −2.12% |
| Q1 2025 | 2025-03-31 | $53.8M | $4.9M | +10.04% |
| Q4 2024 | 2024-12-31 | $46.4M | −$21.6M | −31.80% |
| Q3 2024 | 2024-09-30 | $54.4M | $3.0M | +5.79% |
| Q2 2024 | 2024-06-30 | $55.7M | $10.4M | +23.01% |
| Q1 2024 | 2024-03-31 | $48.9M | $8.9M | +22.23% |
| Q4 2023 | 2023-12-31 | $68.0M | $29.4M | +75.89% |
| Q3 2023 | 2023-09-30 | $51.5M | $19.8M | +62.56% |
| Q2 2023 | 2023-06-30 | $45.3M | $19.0M | +72.05% |
| Q1 2023 | 2023-03-31 | $40.0M | $20.1M | +101.19% |
| Q4 2022 | 2022-12-31 | $38.7M | — | — |
| Q3 2022 | 2022-09-30 | $31.7M | $21.2M | +203.59% |
| Q2 2022 | 2022-06-30 | $26.3M | — | — |
| Q1 2022 | 2022-03-31 | $19.9M | — | — |
| Q3 2021 | 2021-09-30 | $10.4M | — | — |
Prime Medicine operating expenses trends
Over the last five fiscal years, Prime Medicine's operating expenses increased from $6.1M to $213.0M, a change of $206.8M. The latest reported quarter, Q2 2026, shows $44.4M.
About the metric
What operating expenses mean
Operating expenses are the recurring costs of running a company’s business beyond the direct costs used to calculate gross profit. They commonly include selling, general and administrative expenses, research and development, and other operating costs.
Calculation and source
SEC-reported and calculated operating expenses
TickerStat uses operating expenses reported in company SEC filings when available. When a separate total is unavailable, it calculates operating expenses as aligned gross profit minus operating income for the same fiscal period. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Prime Medicine source filings ↗