Prime Medicine annual operating income
2020
2021
2022
2023
2024
2025
Prime Medicine Operating Income Growth & History (PRME)
Prime Medicine's operating income was −$208.3M for fiscal 2025.
View full Prime Medicine company overviewPrime Medicine annual operating income history
| Fiscal year | Period ended | Operating income | Change | Growth |
|---|---|---|---|---|
| 2025 | 2025-12-31 | −$208.3M | −$5.9M | — |
| 2024 | 2024-12-31 | −$202.5M | $2.3M | — |
| 2023 | 2023-12-31 | −$204.8M | −$88.2M | — |
| 2022 | 2022-12-31 | −$116.5M | −$32.1M | — |
| 2021 | 2021-12-31 | −$84.5M | −$83.5M | — |
| 2020 | 2020-12-31 | −$932,000 | — | — |
Prime Medicine quarterly operating income
Q3.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
Q1.26
Q2.26
| Fiscal quarter | Period ended | Operating income | Change | YoY change |
|---|---|---|---|---|
| Q2 2026 | 2026-06-30 | −$43.3M | $10.1M | — |
| Q1 2026 | 2026-03-31 | −$50.7M | $1.7M | — |
| Q4 2025 | 2025-12-31 | −$48.6M | −$4.4M | — |
| Q3 2025 | 2025-09-30 | −$54.0M | $259,000 | — |
| Q2 2025 | 2025-06-30 | −$53.4M | $2.3M | — |
| Q1 2025 | 2025-03-31 | −$52.4M | −$4.1M | — |
| Q4 2024 | 2024-12-31 | −$44.2M | $23.8M | — |
| Q3 2024 | 2024-09-30 | −$54.2M | −$2.8M | — |
| Q2 2024 | 2024-06-30 | −$55.7M | −$10.4M | — |
| Q1 2024 | 2024-03-31 | −$48.3M | −$8.3M | — |
| Q4 2023 | 2023-12-31 | −$68.0M | −$29.4M | — |
| Q3 2023 | 2023-09-30 | −$51.5M | −$19.8M | — |
| Q2 2023 | 2023-06-30 | −$45.3M | −$19.0M | — |
| Q1 2023 | 2023-03-31 | −$40.0M | −$20.1M | — |
| Q4 2022 | 2022-12-31 | −$38.7M | — | — |
| Q3 2022 | 2022-09-30 | −$31.7M | −$21.2M | — |
| Q2 2022 | 2022-06-30 | −$26.3M | — | — |
| Q1 2022 | 2022-03-31 | −$19.9M | — | — |
| Q3 2021 | 2021-09-30 | −$10.4M | — | — |
Prime Medicine operating income trends
Over the last five fiscal years, Prime Medicine's operating income decreased from −$932,000 to −$208.3M, a change of −$207.4M. The latest reported quarter, Q2 2026, shows −$43.3M.
About the metric
What operating income means
Operating income is the profit or loss a company generates from its core business after cost of revenue and operating expenses, but before non-operating items such as interest and income taxes.
Calculation and source
SEC-reported operating income
TickerStat standardizes operating income reported in company SEC filings for aligned fiscal periods. It is not adjusted EBIT, an analyst estimate, or company guidance. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Prime Medicine source filings ↗