Sera Prognostics Return on Equity (ROE) Growth & History (SERA)
Sera Prognostics's return on equity was −51.83% for fiscal 2025.
View full Sera Prognostics company overviewSera Prognostics annual return on equity history
| Fiscal year | Period ended | Return on equity | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | −51.83% | +3.95 pp |
| 2024 | 2024-12-31 | −55.78% | −12.91 pp |
| 2023 | 2023-12-31 | −42.86% | −5.66 pp |
| 2022 | 2022-12-31 | −37.21% | +501.64 pp |
| 2021 | 2021-12-31 | −538.85% | — |
Sera Prognostics quarterly return on equity
| Fiscal quarter | Period ended | Return on equity | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | −14.39% | −5.60 pp |
| Q1 2026 | 2026-03-31 | −11.74% | −0.26 pp |
| Q4 2025 | 2025-12-31 | −10.00% | +6.75 pp |
| Q3 2025 | 2025-09-30 | −9.17% | +4.67 pp |
| Q2 2025 | 2025-06-30 | −8.79% | +4.54 pp |
| Q1 2025 | 2025-03-31 | −11.48% | +0.52 pp |
| Q4 2024 | 2024-12-31 | −16.75% | −5.86 pp |
| Q3 2024 | 2024-09-30 | −13.84% | −4.63 pp |
| Q2 2024 | 2024-06-30 | −13.34% | −1.03 pp |
| Q1 2024 | 2024-03-31 | −12.00% | −0.83 pp |
| Q4 2023 | 2023-12-31 | −10.89% | −1.43 pp |
| Q3 2023 | 2023-09-30 | −9.21% | +0.35 pp |
| Q2 2023 | 2023-06-30 | −12.30% | −2.87 pp |
| Q1 2023 | 2023-03-31 | −11.17% | −1.98 pp |
| Q4 2022 | 2022-12-31 | −9.46% | −0.81 pp |
| Q3 2022 | 2022-09-30 | −9.56% | +128.91 pp |
| Q2 2022 | 2022-06-30 | −9.44% | — |
| Q1 2022 | 2022-03-31 | −9.19% | — |
| Q4 2021 | 2021-12-31 | −8.65% | — |
| Q3 2021 | 2021-09-30 | −138.47% | — |
Sera Prognostics return on equity trends
Between the periods ended 2021-12-31 and 2025-12-31, Sera Prognostics's return on equity increased from −538.85% to −51.83%, a change of +487.02 percentage points. The latest reported quarter, Q2 2026, shows −14.39%.
What return on equity (ROE) means
Return on equity (ROE) measures how much net income a company generates relative to shareholders’ equity. It can help evaluate how efficiently equity capital is used, but unusually high or negative values may reflect leverage, losses, or a small equity base.
How return on equity is calculated
TickerStat calculates ROE as SEC-reported net income divided by average stockholders’ equity at the beginning and end of the fiscal period. Periods with missing or non-positive average equity are omitted. Quarterly ROE uses quarterly net income and is not annualized. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Sera Prognostics source filings ↗