Spyre Therapeutics annual net income
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
Spyre Therapeutics Net Income Growth & History (SYRE)
Spyre Therapeutics's net income was −$155.2M for fiscal 2025.
View full Spyre Therapeutics company overviewSpyre Therapeutics annual net income history
| Fiscal year | Period ended | Net income | Change | Growth |
|---|---|---|---|---|
| 2025 | 2025-12-31 | −$155.2M | $52.8M | — |
| 2024 | 2024-12-31 | −$208.0M | $130.8M | — |
| 2023 | 2023-12-31 | −$338.8M | −$255.0M | — |
| 2022 | 2022-12-31 | −$83.8M | −$18.0M | — |
| 2021 | 2021-12-31 | −$65.8M | $15.1M | — |
| 2020 | 2020-12-31 | −$80.9M | −$2.6M | — |
| 2019 | 2019-12-31 | −$78.3M | −$33.9M | — |
| 2018 | 2018-12-31 | −$44.3M | −$17.1M | — |
| 2017 | 2017-12-31 | −$27.2M | −$5.5M | — |
| 2016 | 2016-12-31 | −$21.7M | −$10.4M | — |
| 2015 | 2015-12-31 | −$11.3M | −$948,000 | — |
| 2014 | 2014-12-31 | −$10.3M | — | — |
Spyre Therapeutics quarterly net income
Q1.15
Q2.15
Q3.15
Q4.15
Q1.16
Q2.16
Q3.16
Q4.16
Q1.17
Q2.17
Q3.17
Q4.17
Q1.18
Q2.18
Q3.18
Q4.18
Q1.19
Q2.19
Q3.19
Q4.19
Q1.20
Q2.20
Q3.20
Q4.20
Q1.21
Q2.21
Q3.21
Q4.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
Q1.26
Q2.26
| Fiscal quarter | Period ended | Net income | Change | YoY change |
|---|---|---|---|---|
| Q2 2026 | 2026-06-30 | −$36.2M | $517,000 | — |
| Q1 2026 | 2026-03-31 | −$69.0M | −$24.2M | — |
| Q4 2025 | 2025-12-31 | −$62.5M | −$6.2M | — |
| Q3 2025 | 2025-09-30 | −$11.2M | $57.8M | — |
| Q2 2025 | 2025-06-30 | −$36.7M | $2.1M | — |
| Q1 2025 | 2025-03-31 | −$44.8M | −$916,000 | — |
| Q4 2024 | 2024-12-31 | −$56.3M | $6.9M | — |
| Q3 2024 | 2024-09-30 | −$69.0M | −$28.9M | — |
| Q2 2024 | 2024-06-30 | −$38.8M | $178.2M | — |
| Q1 2024 | 2024-03-31 | −$43.9M | −$25.4M | — |
| Q4 2023 | 2023-12-31 | −$63.2M | −$44.4M | — |
| Q3 2023 | 2023-09-30 | −$40.1M | −$21.9M | — |
| Q2 2023 | 2023-06-30 | −$217.1M | −$194.8M | — |
| Q1 2023 | 2023-03-31 | −$18.4M | $6.0M | — |
| Q4 2022 | 2022-12-31 | −$18.8M | $1.6M | — |
| Q3 2022 | 2022-09-30 | −$18.2M | $2.1M | — |
| Q2 2022 | 2022-06-30 | −$22.3M | −$15.5M | — |
| Q1 2022 | 2022-03-31 | −$24.4M | −$6.2M | — |
| Q4 2021 | 2021-12-31 | −$20.4M | $2.3M | — |
| Q3 2021 | 2021-09-30 | −$20.3M | −$2.3M | — |
| Q2 2021 | 2021-06-30 | −$6.8M | $14.6M | — |
| Q1 2021 | 2021-03-31 | −$18.2M | $510,000 | — |
| Q4 2020 | 2020-12-31 | −$22.7M | −$1.2M | — |
| Q3 2020 | 2020-09-30 | −$18.0M | $3.5M | — |
| Q2 2020 | 2020-06-30 | −$21.4M | −$3.4M | — |
| Q1 2020 | 2020-03-31 | −$18.7M | −$1.6M | — |
| Q4 2019 | 2019-12-31 | −$21.5M | −$6.6M | — |
| Q3 2019 | 2019-09-30 | −$21.6M | −$9.7M | — |
| Q2 2019 | 2019-06-30 | −$18.0M | −$8.6M | — |
| Q1 2019 | 2019-03-31 | −$17.2M | −$9.0M | — |
| Q4 2018 | 2018-12-31 | −$14.9M | −$8.4M | — |
| Q3 2018 | 2018-09-30 | −$11.9M | −$4.0M | — |
| Q2 2018 | 2018-06-30 | −$9.4M | −$2.8M | — |
| Q1 2018 | 2018-03-31 | −$8.1M | −$1.9M | — |
| Q4 2017 | 2017-12-31 | −$6.5M | −$1.0M | — |
| Q3 2017 | 2017-09-30 | −$7.9M | −$1.6M | — |
| Q2 2017 | 2017-06-30 | −$6.6M | −$1.2M | — |
| Q1 2017 | 2017-03-31 | −$6.2M | −$1.7M | — |
| Q4 2016 | 2016-12-31 | −$5.5M | −$1.5M | — |
| Q3 2016 | 2016-09-30 | −$6.2M | −$2.8M | — |
| Q2 2016 | 2016-06-30 | −$5.4M | −$4.0M | — |
| Q1 2016 | 2016-03-31 | −$4.5M | −$2.1M | — |
| Q4 2015 | 2015-12-31 | −$4.0M | — | — |
| Q3 2015 | 2015-09-30 | −$3.4M | — | — |
| Q2 2015 | 2015-06-30 | −$1.4M | — | — |
| Q1 2015 | 2015-03-31 | −$2.5M | — | — |
Spyre Therapeutics net income trends
Over the last five fiscal years, Spyre Therapeutics's net income decreased from −$80.9M to −$155.2M, a change of −$74.3M. The latest reported quarter, Q2 2026, shows −$36.2M.
About the metric
What net income means
Net income is a company’s bottom-line profit or loss after operating costs, interest, taxes, and other reported income and expenses. It shows how much of a company’s revenue ultimately remained as earnings, or how large its loss was, during a fiscal period.
Calculation and source
SEC-reported net income
TickerStat standardizes consolidated net income or profit and loss reported in company SEC filings for aligned fiscal periods. It is not adjusted earnings, an analyst estimate, or company guidance. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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