Vertex Pharmaceuticals annual operating margin
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Vertex Pharmaceuticals Operating Margin Growth & History (VRTX)
Vertex Pharmaceuticals's operating margin was 34.77% for fiscal 2025.
View full Vertex Pharmaceuticals company overviewVertex Pharmaceuticals annual operating margin history
| Fiscal year | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | 34.77% | +36.89 pp |
| 2024 | 2024-12-31 | −2.11% | −40.94 pp |
| 2023 | 2023-12-31 | 38.83% | −9.40 pp |
| 2022 | 2022-12-31 | 48.23% | +11.50 pp |
| 2021 | 2021-12-31 | 36.73% | −9.30 pp |
| 2020 | 2020-12-31 | 46.03% | +17.26 pp |
| 2019 | 2019-12-31 | 28.77% | +7.93 pp |
| 2018 | 2018-12-31 | 20.84% | +15.89 pp |
| 2017 | 2017-12-31 | 4.95% | +4.37 pp |
| 2016 | 2016-12-31 | 0.58% | +45.81 pp |
| 2015 | 2015-12-31 | −45.23% | +74.07 pp |
| 2014 | 2014-12-31 | −119.30% | −68.96 pp |
| 2013 | 2013-12-31 | −50.33% | −53.39 pp |
| 2012 | 2012-12-31 | 3.06% | −5.01 pp |
| 2011 | 2011-12-31 | 8.07% | +493.58 pp |
| 2010 | 2010-12-31 | −485.51% | +117.12 pp |
| 2009 | 2009-12-31 | −602.63% | −338.98 pp |
| 2008 | 2008-12-31 | −263.65% | — |
Vertex Pharmaceuticals quarterly operating margin
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| Fiscal quarter | Period ended | Operating margin | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | 37.40% | −1.43 pp |
| Q1 2026 | 2026-03-31 | 38.10% | +15.36 pp |
| Q4 2025 | 2025-12-31 | 37.80% | +2.57 pp |
| Q3 2025 | 2025-09-30 | 38.56% | −1.71 pp |
| Q2 2025 | 2025-06-30 | 38.83% | +171.68 pp |
| Q1 2025 | 2025-03-31 | 22.75% | −19.61 pp |
| Q4 2024 | 2024-12-31 | 35.23% | −4.03 pp |
| Q3 2024 | 2024-09-30 | 40.27% | −1.53 pp |
| Q2 2024 | 2024-06-30 | −132.85% | −174.02 pp |
| Q1 2024 | 2024-03-31 | 42.35% | +9.55 pp |
| Q4 2023 | 2023-12-31 | 39.26% | −5.62 pp |
| Q3 2023 | 2023-09-30 | 41.80% | −6.47 pp |
| Q2 2023 | 2023-06-30 | 41.17% | −9.21 pp |
| Q1 2023 | 2023-03-31 | 32.80% | −16.82 pp |
| Q4 2022 | 2022-12-31 | 44.88% | +2.53 pp |
| Q3 2022 | 2022-09-30 | 48.27% | −4.88 pp |
| Q2 2022 | 2022-06-30 | 50.37% | +52.49 pp |
| Q1 2022 | 2022-03-31 | 49.63% | −1.86 pp |
| Q4 2021 | 2021-12-31 | 42.35% | −3.47 pp |
| Q3 2021 | 2021-09-30 | 53.15% | +9.45 pp |
| Q2 2021 | 2021-06-30 | −2.11% | −49.21 pp |
| Q1 2021 | 2021-03-31 | 51.49% | +3.95 pp |
| Q4 2020 | 2020-12-31 | 45.82% | +6.80 pp |
| Q3 2020 | 2020-09-30 | 43.70% | +33.24 pp |
| Q2 2020 | 2020-06-30 | 47.10% | +18.42 pp |
| Q1 2020 | 2020-03-31 | 47.54% | +15.29 pp |
| Q4 2019 | 2019-12-31 | 39.02% | +24.34 pp |
| Q3 2019 | 2019-09-30 | 10.46% | −15.75 pp |
| Q2 2019 | 2019-06-30 | 28.68% | +5.70 pp |
| Q1 2019 | 2019-03-31 | 32.25% | +12.13 pp |
| Q4 2018 | 2018-12-31 | 14.68% | −4.62 pp |
| Q3 2018 | 2018-09-30 | 26.21% | +82.61 pp |
| Q2 2018 | 2018-06-30 | 22.98% | +13.30 pp |
| Q1 2018 | 2018-03-31 | 20.12% | −17.78 pp |
| Q4 2017 | 2017-12-31 | 19.30% | +10.65 pp |
| Q3 2017 | 2017-09-30 | −56.39% | −51.87 pp |
| Q2 2017 | 2017-06-30 | 9.69% | +8.91 pp |
| Q1 2017 | 2017-03-31 | 37.89% | +41.49 pp |
| Q4 2016 | 2016-12-31 | 8.64% | +21.49 pp |
| Q3 2016 | 2016-09-30 | −4.53% | +18.08 pp |
| Q2 2016 | 2016-06-30 | 0.78% | +103.84 pp |
| Q1 2016 | 2016-03-31 | −3.60% | +120.57 pp |
| Q4 2015 | 2015-12-31 | −12.85% | +93.42 pp |
| Q3 2015 | 2015-09-30 | −22.60% | +56.85 pp |
| Q2 2015 | 2015-06-30 | −103.06% | +27.37 pp |
| Q1 2015 | 2015-03-31 | −124.17% | +58.22 pp |
| Q4 2014 | 2014-12-31 | −106.27% | −108.77 pp |
| Q3 2014 | 2014-09-30 | −79.45% | −23.72 pp |
| Q2 2014 | 2014-06-30 | −130.43% | −112.11 pp |
| Q1 2014 | 2014-03-31 | −182.39% | −48.91 pp |
| Q4 2013 | 2013-12-31 | 2.50% | +12.40 pp |
| Q3 2013 | 2013-09-30 | −55.73% | −55.41 pp |
| Q2 2013 | 2013-06-30 | −18.32% | −15.75 pp |
| Q1 2013 | 2013-03-31 | −133.47% | −154.36 pp |
| Q4 2012 | 2012-12-31 | −9.90% | −49.65 pp |
| Q3 2012 | 2012-09-30 | −0.32% | −33.04 pp |
| Q2 2012 | 2012-06-30 | −2.57% | +142.40 pp |
| Q1 2012 | 2012-03-31 | 20.89% | +237.96 pp |
| Q4 2011 | 2011-12-31 | 39.75% | +294.06 pp |
| Q3 2011 | 2011-09-30 | 32.72% | +871.50 pp |
| Q2 2011 | 2011-06-30 | −144.98% | +391.27 pp |
| Q1 2011 | 2011-03-31 | −217.07% | +497.55 pp |
| Q4 2010 | 2010-12-31 | −254.31% | +178.63 pp |
| Q3 2010 | 2010-09-30 | −838.78% | −244.83 pp |
| Q2 2010 | 2010-06-30 | −536.25% | +288.17 pp |
| Q1 2010 | 2010-03-31 | −714.62% | −39.47 pp |
| Q4 2009 | 2009-12-31 | −432.94% | — |
| Q3 2009 | 2009-09-30 | −593.95% | — |
| Q2 2009 | 2009-06-30 | −824.42% | — |
| Q1 2009 | 2009-03-31 | −675.14% | — |
Vertex Pharmaceuticals operating margin trends
Over the last five reported fiscal years, Vertex Pharmaceuticals's operating margin decreased from 46.03% to 34.77%, a change of −11.25 percentage points. The latest reported quarter, Q2 2026, shows 37.40%.
About the metric
What operating margin means
Operating margin measures the percentage of revenue left after operating costs and expenses. It shows how much operating profit a company generates from each dollar of revenue.
Calculation and source
How operating margin is calculated
TickerStat calculates operating margin as SEC-reported operating income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Vertex Pharmaceuticals filings at SEC.gov ↗