Revenue
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $30.9M | $10.0M | $0 | $2.6M | $2.1M | $88.5M | $17.5M | $26.7M | — | — | — | — | — | — | — |
| Gross profit | $25.6M | $10.0M | $0 | $2.6M | — | — | — | $26.6M | — | — | — | — | — | — | — |
| Gross margin | 82.86% | 100.00% | — | 100.00% | — | — | — | 99.38% | — | — | — | — | — | — | — |
| Research & development | $114.6M | $81.3M | $61.4M | $50.6M | $39.3M | $41.4M | $45.8M | $43.6M | $46.4M | $19.8M | $40.6M | $35.4M | $25.9M | $21.7M | $9.9M |
| Operating expenses | $201.0M | $125.0M | $92.1M | $75.5M | $63.5M | $137.9M | $149.8M | $121.5M | $67.8M | $37.0M | $58.2M | $53.6M | $41.4M | $32.2M | $13.7M |
| Operating income | −$170.1M | −$115.0M | −$92.1M | −$72.9M | −$61.4M | −$49.4M | −$132.3M | −$94.8M | −$67.8M | −$37.0M | −$58.2M | −$53.6M | −$41.4M | −$32.2M | −$13.7M |
| Operating margin | −550.33% | −1,149.56% | — | −2,809.59% | −2,991.18% | −55.76% | −758.14% | −354.75% | — | — | — | — | — | — | — |
| EBITDA | −$169.4M | −$114.9M | −$92.0M | −$72.8M | −$61.2M | −$48.0M | −$130.3M | −$93.4M | −$67.2M | −$36.3M | −$57.4M | −$53.2M | −$41.2M | −$32.0M | −$13.6M |
| EBITDA margin | −547.98% | −1,149.30% | — | −2,805.05% | −2,981.15% | −54.27% | −746.69% | −349.44% | — | — | — | — | — | — | — |
| Net income | −$209.5M | −$130.6M | −$87.4M | −$73.8M | −$71.2M | −$67.7M | −$149.2M | −$72.4M | −$67.8M | −$36.4M | −$57.9M | −$53.4M | −$41.2M | −$32.0M | −$13.7M |
| Net profit margin | −677.59% | −1,306.37% | — | −2,843.30% | −3,468.10% | −76.51% | −854.77% | −271.11% | — | — | — | — | — | — | — |
| Basic EPSper basic share | -$3.02 | -$3.66 | -$3.96 | -$4.57 | -$4.90 | -$5.28 | -$24.00 | -$13.44 | -$21.12 | -$11.88 | -$19.32 | -$24.84 | -$21.84 | -$20.40 | -$127.08 |
| Diluted EPSper diluted share | -$3.02 | -$3.66 | -$3.96 | -$4.57 | -$4.90 | -$5.28 | -$24.00 | -$16.44 | -$21.12 | -$11.88 | -$19.32 | -$24.84 | -$21.84 | -$20.40 | -$127.08 |
Reported shareholders
| Holder | % owned |
|---|---|
BlackRock, Inc. | 10.16%9.19M shares |
Nantahala Capital Management, LLC | 7.92%7.17M shares |
ARMISTICE CAPITAL, LLC | 7.76%7.02M shares |
RTW INVESTMENTS, LP | 7.33%6.64M shares |
Deep Track Capital, LP | 6.34%5.74M shares |
STATE STREET CORP | 5.67%5.13M shares |
Rosalind Advisors, Inc. | 4.41%3.99M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.26%3.85M shares |
Stonepine Capital Management, LLC | 3.70%3.35M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 3.61%3.27M shares |
Foresite Capital Management VI LLC | 3.48%3.15M shares |
GOLDMAN SACHS GROUP INC | 3.01%2.72M shares |
BAKER BROS. ADVISORS LP | 2.76%2.5M shares |
Alyeska Investment Group, L.P. | 2.53%2.29M shares |
MILLENNIUM MANAGEMENT LLC | 2.30%2.08M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.29%2.07M shares |
AIGH Capital Management LLC | 2.13%1.93M shares |
Opaleye Management Inc. | 1.99%1.8M shares |
Balyasny Asset Management L.P. | 1.86%1.69M shares |
Qube Research & Technologies Ltd | 1.80%1.63M shares |
Percentages use 90.48M shares of this listed class outstanding on Jun 30, 2026.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 22, 2026Form 4 · 10b5-1 | Paterson DanPresident and CEO | SellCommon Stock | 20.9K | $4.18 | $87.2K | 591.2K |
| Jun 22, 2026Form 4 · 10b5-1 | Calkins DanielChief Financial Officer | SellCommon Stock | 57 | $4.13 | $235.41 | 117.2K |
| Jun 22, 2026Form 4 · 10b5-1 | Calkins DanielChief Financial Officer | SellCommon Stock | 4.0K | $4.18 | $16.9K | 117.3K |
| May 4, 2026Form 4 · 10b5-1 | Paterson DanPresident and CEO | SellCommon Stock | 806 | $5.82 | $4.7K | 612.1K |
| Feb 4, 2026Form 4 · 10b5-1 | Paterson DanPresident and CEO | SellCommon Stock | 970 | $6.69 | $6.5K | 612.9K |