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Vertex adds detailed kidney-response data and launches patient-experience trial

Vertex ($VRTX) released additional Phase 3 RAINIER findings for povetacicept in IgA nephropathy. At week 36, 42.2% of treated participants achieved a urine protein-to-creatinine ratio below 0.5 grams per gram, compared with 6.2% receiving placebo. The company reported consistent effects across patient groups, including a 54.2% proteinuria reduction versus placebo in North America. Both groups also received optimized supportive care. The new details supplement the previously reported primary resu

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