Revenue
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — | — |
| Research & development | $92.9M | $115.4M | $103.8M | $112.5M | $73.9M | $29.6M |
| Operating expenses | $140.9M | $179.6M | $141.5M | $247.4M | $124.9M | $109.3M |
| Operating income | −$140.9M | −$179.6M | −$141.5M | −$247.4M | −$124.9M | −$109.3M |
| EBITDA | −$137.8M | −$175.8M | −$137.8M | −$244.8M | −$124.1M | −$108.7M |
| Net income | −$124.5M | −$161.7M | −$125.0M | −$242.8M | −$122.8M | −$101.7M |
| Basic EPSper basic share | -$0.44 | -$0.69 | -$0.83 | -$1.99 | -$1.85 | -$4.83 |
| Diluted EPSper diluted share | -$0.44 | -$0.69 | -$0.83 | -$1.99 | -$1.85 | -$4.83 |
Reported shareholders
| Holder | % owned |
|---|---|
Frazier Life Sciences Management, L.P. | 7.99%24.98M shares |
T. Rowe Price Investment Management, Inc. | 6.78%21.19M shares |
BlackRock, Inc. | 6.77%21.15M shares |
RTW INVESTMENTS, LP | 5.74%17.95M shares |
Venrock Adviser, LLC | 5.72%17.89M shares |
STATE STREET CORP | 3.90%12.18M shares |
Logos Global Management LP | 3.89%12.15M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 3.65%11.4M shares |
Siren, L.L.C. | 3.65%11.4M shares |
Paradigm Biocapital Advisors LP | 3.06%9.55M shares |
ARCH Venture Management, LLC | 2.27%7.09M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.08%6.5M shares |
PRICE T ROWE ASSOCIATES INC /MD/ | 2.01%6.27M shares |
Cormorant Asset Management, LP | 1.92%6M shares |
Affinity Asset Advisors, LLC | 1.68%5.25M shares |
Vivo Capital, LLC | 1.32%4.13M shares |
ALLIANCEBERNSTEIN L.P. | 1.32%4.12M shares |
GOLDMAN SACHS GROUP INC | 1.22%3.82M shares |
BANK OF AMERICA CORP /DE/ | 0.98%3.05M shares |
FMR LLC | 0.92%2.88M shares |
Percentages use 312.56M shares of this listed class outstanding on Jun 30, 2026.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Apr 1, 2026Form 4 · 10b5-1 | Garner EbunChief Legal Officer | SellCommon Stock | 80.0K | $16.40 | $1.31M | 25.1K |
| Mar 4, 2026Form 4 · 10b5-1 | Morris ShannonChief Medical Officer | SellCommon Stock | 20.0K | $15.04 | $300.8K | 0 |
| Jan 7, 2026Form 4 · 10b5-1 | Garner EbunGeneral Counsel & Corp. Sec. | SellCommon Stock | 120.0K | $5.59 | $670.8K | 25.1K |