Revenue
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $48.19B | $48.30B | $45.01B | $46.16B | $46.38B | $42.52B | $26.14B | $22.56B | $20.78B | $19.43B | $16.56B | $15.88B | $16.39B | $17.62B | $21.24B | $19.48B | $18.81B | $17.71B | $15.62B |
| Gross profit | $34.26B | $34.33B | $34.31B | $36.02B | $36.45B | $30.75B | $18.07B | $16.09B | $14.68B | $14.48B | $12.65B | $11.95B | $11.77B | $13.01B | $15.65B | $14.21B | $13.67B | $12.40B | $10.70B |
| Gross margin | 71.08% | 71.08% | 76.24% | 78.04% | 78.57% | 72.31% | 69.10% | 71.34% | 70.67% | 74.54% | 76.39% | 75.24% | 71.81% | 73.84% | 73.65% | 72.92% | 72.67% | 69.99% | 68.50% |
| Research & development | $9.95B | $11.16B | $9.30B | $9.51B | $10.20B | $10.05B | $6.15B | $6.33B | $6.47B | $5.01B | $5.92B | $4.53B | $3.73B | $3.90B | $3.84B | $3.57B | $3.65B | $3.51B | $3.16B |
| Operating expenses | $38.87B | $56.68B | $36.57B | $38.45B | $38.29B | $49.39B | $21.17B | $16.59B | $15.64B | $13.51B | $14.48B | $13.50B | $13.49B | $15.28B | $14.26B | $13.41B | $13.21B | $12.94B | $13.09B |
| Operating income | $9.33B | −$8.38B | $8.44B | $7.71B | $8.10B | −$6.87B | $4.97B | $5.97B | $5.13B | $5.92B | $2.08B | $2.38B | $2.89B | $2.34B | $6.98B | $6.07B | $5.60B | $4.78B | $2.52B |
| Operating margin | 19.36% | −17.35% | 18.75% | 16.71% | 17.46% | −16.16% | 19.03% | 26.45% | 24.70% | 30.45% | 12.54% | 14.99% | 17.64% | 13.28% | 32.86% | 31.16% | 29.79% | 26.96% | 16.16% |
| EBITDA | $13.34B | $1.22B | $18.20B | $17.99B | $18.78B | $3.51B | $6.72B | $6.61B | $5.92B | $6.30B | $2.45B | $2.85B | $3.65B | $3.02B | $7.61B | $6.68B | $6.07B | $5.34B | $3.06B |
| EBITDA margin | 27.68% | 2.53% | 40.44% | 38.97% | 40.50% | 8.25% | 25.71% | 29.28% | 28.49% | 32.41% | 14.81% | 17.94% | 22.30% | 17.14% | 35.82% | 34.27% | 32.28% | 30.13% | 19.63% |
| Net income | $7.05B | −$8.95B | $8.03B | $6.33B | $6.99B | −$9.02B | $3.44B | $4.92B | $1.01B | $4.46B | $1.56B | $2.00B | $2.56B | $1.96B | $3.71B | $3.10B | $10.61B | $5.25B | $2.17B |
| Net profit margin | 14.64% | −18.53% | 17.83% | 13.71% | 15.08% | −21.20% | 13.15% | 21.81% | 4.85% | 22.94% | 9.45% | 12.62% | 15.64% | 11.12% | 17.46% | 15.92% | 56.42% | 29.62% | 13.86% |
| Basic EPSper basic share | $3.47 | -$4.41 | $3.88 | $2.97 | $3.15 | -$3.99 | $2.02 | $3.01 | $0.61 | $2.67 | $0.94 | $1.21 | $1.56 | $1.17 | $2.18 | $1.80 | $5.35 | $2.64 | $1.09 |
| Diluted EPSper diluted share | $3.46 | -$4.41 | $3.86 | $2.95 | $3.12 | -$3.99 | $2.01 | $3.01 | $0.61 | $2.65 | $0.93 | $1.20 | $1.54 | $1.16 | $2.16 | $1.79 | $5.34 | $2.62 | $1.09 |
Reported shareholders
Reported holdings Number of shares
| Holder | Shares held |
|---|---|
BlackRock, Inc. | 180.38M |
VANGUARD CAPITAL MANAGEMENT LLC | 133.34M |
STATE STREET CORP | 102.41M |
JPMORGAN CHASE & CO | 71.71M |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 67.6M |
GEODE CAPITAL MANAGEMENT, LLC | 56.44M |
VANGUARD PORTFOLIO MANAGEMENT LLC | 46.87M |
NORGES BANK | 36.87M |
BANK OF AMERICA CORP /DE/ | 34.05M |
PRICE T ROWE ASSOCIATES INC /MD/ | 31.71M |
MORGAN STANLEY | 29.01M |
AQR CAPITAL MANAGEMENT LLC | 27.36M |
AMERIPRISE FINANCIAL INC | 26.67M |
PRIMECAP MANAGEMENT CO/CA/ | 24.92M |
NORTHERN TRUST CORP | 24.92M |
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 22.84M |
Bank of New York Mellon Corp | 21.82M |
Independent Franchise Partners LLP | 21.79M |
DIMENSIONAL FUND ADVISORS LP | 19.69M |
Legal & General Group Plc | 17.02M |
Bars compare reported share counts. A matching total for this share class and reporting period is unavailable, so percentages are not shown.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Apr 1, 2026Form 4 | Elkins David VEVP, Chief Financial Officer | SellCommon Stock, $0.10 par value | 4.5K | $62.05 | $278.0K | 159.2K |
| Apr 1, 2026Form 4 | Elkins David VEVP, Chief Financial Officer | SellCommon Stock, $0.10 par value | 25.5K | $61.60 | $1.57M | 163.7K |
| Sep 2, 2025Form 4 | Elkins David VEVP, Chief Financial Officer | SellCommon Stock, $0.10 par value | 56.0K | $47.33 | $2.65M | 167.4K |
| Aug 2, 2025Form 4 | Short Bartie WendyEVP, Corporate Affairs | SellCommon Stock, $0.10 par value | 378 | $44.23 | $16.7K | 5.1K |
| May 9, 2025Form 4 | Hickey BenjaminPresident, RayzeBio Org. | SellCommon Stock, $0.10 par value · indirect | 97.39 | $38.01 | $3.7K | 0 |
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