Karyopharm Therapeutics annual operating expenses
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Karyopharm Therapeutics Operating Expenses Growth & History (KPTI)
Karyopharm Therapeutics's operating expenses was $236.8M for fiscal 2025.
View full Karyopharm Therapeutics company overviewKaryopharm Therapeutics annual operating expenses history
| Fiscal year | Period ended | Operating expenses | Change | Growth |
|---|---|---|---|---|
| 2025 | 2025-12-31 | $236.8M | −$27.9M | −10.54% |
| 2024 | 2024-12-31 | $264.7M | −$10.9M | −3.95% |
| 2023 | 2023-12-31 | $275.6M | −$23.7M | −7.92% |
| 2022 | 2022-12-31 | $299.3M | −$8.8M | −2.86% |
| 2021 | 2021-12-31 | $308.1M | $28.2M | +10.06% |
| 2020 | 2020-12-31 | $279.9M | $49.8M | +21.62% |
| 2019 | 2019-12-31 | $230.2M | $19.9M | +9.49% |
| 2018 | 2018-12-31 | $210.2M | $78.1M | +59.08% |
| 2017 | 2017-12-31 | $132.1M | $21.3M | +19.17% |
| 2016 | 2016-12-31 | $110.9M | −$8.4M | −7.07% |
| 2015 | 2015-12-31 | $119.3M | $43.3M | +56.85% |
| 2014 | 2014-12-31 | $76.1M | $41.7M | +121.55% |
| 2013 | 2013-12-31 | $34.3M | $17.8M | +107.80% |
| 2012 | 2012-12-31 | $16.5M | $6.1M | +57.93% |
| 2011 | 2011-12-31 | $10.5M | — | — |
Karyopharm Therapeutics quarterly operating expenses
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| Fiscal quarter | Period ended | Operating expenses | Change | YoY change |
|---|---|---|---|---|
| Q2 2026 | 2026-06-30 | $56.0M | −$6.4M | −10.20% |
| Q1 2026 | 2026-03-31 | $61.8M | −$1.4M | −2.28% |
| Q4 2025 | 2025-12-31 | $51.9M | −$9.9M | −16.01% |
| Q3 2025 | 2025-09-30 | $59.3M | −$5.8M | −8.92% |
| Q2 2025 | 2025-06-30 | $62.3M | −$8.6M | −12.11% |
| Q1 2025 | 2025-03-31 | $63.3M | −$3.6M | −5.40% |
| Q4 2024 | 2024-12-31 | $61.8M | −$9.7M | −13.60% |
| Q3 2024 | 2024-09-30 | $65.1M | −$2.2M | −3.27% |
| Q2 2024 | 2024-06-30 | $70.9M | $3.8M | +5.59% |
| Q1 2024 | 2024-03-31 | $66.9M | −$2.7M | −3.90% |
| Q4 2023 | 2023-12-31 | $71.6M | $4.1M | +6.09% |
| Q3 2023 | 2023-09-30 | $67.3M | $285,000 | +0.43% |
| Q2 2023 | 2023-06-30 | $67.2M | −$15.4M | −18.69% |
| Q1 2023 | 2023-03-31 | $69.6M | −$12.7M | −15.39% |
| Q4 2022 | 2022-12-31 | $67.4M | −$11.9M | −14.95% |
| Q3 2022 | 2022-09-30 | $67.0M | −$14.5M | −17.81% |
| Q2 2022 | 2022-06-30 | $82.6M | $10.9M | +15.27% |
| Q1 2022 | 2022-03-31 | $82.3M | $6.6M | +8.76% |
| Q4 2021 | 2021-12-31 | $79.3M | $7.1M | +9.90% |
| Q3 2021 | 2021-09-30 | $81.5M | $13.1M | +19.08% |
| Q2 2021 | 2021-06-30 | $71.6M | −$2.2M | −2.96% |
| Q1 2021 | 2021-03-31 | $75.6M | $10.1M | +15.48% |
| Q4 2020 | 2020-12-31 | $72.2M | $10.8M | +17.61% |
| Q3 2020 | 2020-09-30 | $68.4M | $15.9M | +30.24% |
| Q2 2020 | 2020-06-30 | $73.8M | $22.7M | +44.26% |
| Q1 2020 | 2020-03-31 | $65.5M | $417,000 | +0.64% |
| Q4 2019 | 2019-12-31 | $61.4M | $3.7M | +6.42% |
| Q3 2019 | 2019-09-30 | $52.5M | $3.2M | +6.39% |
| Q2 2019 | 2019-06-30 | $51.2M | −$3.0M | −5.61% |
| Q1 2019 | 2019-03-31 | $65.1M | $16.1M | +32.97% |
| Q4 2018 | 2018-12-31 | $57.7M | $16.7M | +40.68% |
| Q3 2018 | 2018-09-30 | $49.4M | $18.3M | +59.05% |
| Q2 2018 | 2018-06-30 | $54.2M | $24.5M | +82.23% |
| Q1 2018 | 2018-03-31 | $48.9M | $18.6M | +61.27% |
| Q4 2017 | 2017-12-31 | $41.0M | $13.8M | +50.62% |
| Q3 2017 | 2017-09-30 | $31.1M | $5.3M | +20.41% |
| Q2 2017 | 2017-06-30 | $29.8M | −$780,000 | −2.55% |
| Q1 2017 | 2017-03-31 | $30.3M | $3.0M | +10.96% |
| Q4 2016 | 2016-12-31 | $27.2M | −$2.1M | −7.21% |
| Q3 2016 | 2016-09-30 | $25.8M | −$4.9M | −15.95% |
| Q2 2016 | 2016-06-30 | $30.5M | −$2.6M | −7.92% |
| Q1 2016 | 2016-03-31 | $27.3M | $1.2M | +4.59% |
| Q4 2015 | 2015-12-31 | $29.3M | $3.4M | +12.98% |
| Q3 2015 | 2015-09-30 | $30.7M | $10.9M | +55.25% |
| Q2 2015 | 2015-06-30 | $33.2M | $16.7M | +101.37% |
| Q1 2015 | 2015-03-31 | $26.1M | $12.3M | +88.36% |
| Q4 2014 | 2014-12-31 | $26.0M | $13.8M | +113.31% |
| Q3 2014 | 2014-09-30 | $19.8M | $10.4M | +112.05% |
| Q2 2014 | 2014-06-30 | $16.5M | $9.5M | +135.17% |
| Q1 2014 | 2014-03-31 | $13.9M | $8.0M | +137.56% |
| Q4 2013 | 2013-12-31 | $12.2M | $7.9M | +184.92% |
| Q3 2013 | 2013-09-30 | $9.3M | $5.7M | +154.05% |
| Q2 2013 | 2013-06-30 | $7.0M | $2.4M | +53.34% |
| Q1 2013 | 2013-03-31 | $5.8M | $1.8M | +45.48% |
| Q4 2012 | 2012-12-31 | $4.3M | — | — |
| Q3 2012 | 2012-09-30 | $3.7M | — | — |
| Q2 2012 | 2012-06-30 | $4.6M | — | — |
| Q1 2012 | 2012-03-31 | $4.0M | — | — |
Karyopharm Therapeutics operating expenses trends
Over the last five fiscal years, Karyopharm Therapeutics's operating expenses decreased from $279.9M to $236.8M, a change of −$43.2M. The latest reported quarter, Q2 2026, shows $56.0M.
About the metric
What operating expenses mean
Operating expenses are the recurring costs of running a company’s business beyond the direct costs used to calculate gross profit. They commonly include selling, general and administrative expenses, research and development, and other operating costs.
Calculation and source
SEC-reported and calculated operating expenses
TickerStat uses operating expenses reported in company SEC filings when available. When a separate total is unavailable, it calculates operating expenses as aligned gross profit minus operating income for the same fiscal period. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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