Spyre Therapeutics annual r&d spending
2014
2015
2016
2017
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2021
2022
2023
2024
2025
Spyre Therapeutics R&D Spending Growth & History (SYRE)
Spyre Therapeutics's r&d spending was $171.7M for fiscal 2025.
View full Spyre Therapeutics company overviewSpyre Therapeutics annual r&d spending history
| Fiscal year | Period ended | R&D spending | Change | Growth |
|---|---|---|---|---|
| 2025 | 2025-12-31 | $171.7M | $8.9M | +5.44% |
| 2024 | 2024-12-31 | $162.8M | $73.3M | +81.88% |
| 2023 | 2023-12-31 | $89.5M | $30.9M | +52.79% |
| 2022 | 2022-12-31 | $58.6M | $1.5M | +2.65% |
| 2021 | 2021-12-31 | $57.1M | −$2.6M | −4.31% |
| 2020 | 2020-12-31 | $59.6M | −$5.0M | −7.68% |
| 2019 | 2019-12-31 | $64.6M | $27.9M | +75.93% |
| 2018 | 2018-12-31 | $36.7M | $13.9M | +60.94% |
| 2017 | 2017-12-31 | $22.8M | $4.7M | +25.75% |
| 2016 | 2016-12-31 | $18.1M | $6.7M | +58.41% |
| 2015 | 2015-12-31 | $11.5M | $4.6M | +67.69% |
| 2014 | 2014-12-31 | $6.8M | — | — |
Spyre Therapeutics quarterly r&d spending
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Q2.26
| Fiscal quarter | Period ended | R&D spending | Change | YoY change |
|---|---|---|---|---|
| Q2 2026 | 2026-06-30 | $65.5M | $25.4M | +63.17% |
| Q1 2026 | 2026-03-31 | $60.4M | $18.8M | +45.14% |
| Q4 2025 | 2025-12-31 | $44.6M | −$5.8M | −11.58% |
| Q3 2025 | 2025-09-30 | $45.2M | $503,000 | +1.12% |
| Q2 2025 | 2025-06-30 | $40.1M | $7.5M | +23.01% |
| Q1 2025 | 2025-03-31 | $41.6M | $6.7M | +19.17% |
| Q4 2024 | 2024-12-31 | $50.5M | $16.8M | +49.88% |
| Q3 2024 | 2024-09-30 | $44.7M | $20.1M | +81.44% |
| Q2 2024 | 2024-06-30 | $32.6M | $15.3M | +87.71% |
| Q1 2024 | 2024-03-31 | $34.9M | $21.2M | +153.54% |
| Q4 2023 | 2023-12-31 | $33.7M | $19.4M | +136.35% |
| Q3 2023 | 2023-09-30 | $24.7M | $12.7M | +105.89% |
| Q2 2023 | 2023-06-30 | $17.4M | $2.0M | +13.09% |
| Q1 2023 | 2023-03-31 | $13.8M | −$3.2M | −18.86% |
| Q4 2022 | 2022-12-31 | $14.3M | −$2.5M | −15.08% |
| Q3 2022 | 2022-09-30 | $12.0M | −$2.9M | −19.36% |
| Q2 2022 | 2022-06-30 | $15.4M | $1.8M | +13.21% |
| Q1 2022 | 2022-03-31 | $17.0M | $5.1M | +43.21% |
| Q4 2021 | 2021-12-31 | $16.8M | $1.0M | +6.51% |
| Q3 2021 | 2021-09-30 | $14.9M | $2.4M | +19.29% |
| Q2 2021 | 2021-06-30 | $13.6M | −$3.3M | −19.50% |
| Q1 2021 | 2021-03-31 | $11.9M | −$2.7M | −18.59% |
| Q4 2020 | 2020-12-31 | $15.8M | −$1.8M | −10.30% |
| Q3 2020 | 2020-09-30 | $12.5M | −$5.4M | −30.20% |
| Q2 2020 | 2020-06-30 | $16.9M | $2.1M | +13.93% |
| Q1 2020 | 2020-03-31 | $14.6M | $173,000 | +1.20% |
| Q4 2019 | 2019-12-31 | $17.6M | $5.8M | +48.89% |
| Q3 2019 | 2019-09-30 | $17.8M | $8.9M | +99.79% |
| Q2 2019 | 2019-06-30 | $14.8M | $5.7M | +62.31% |
| Q1 2019 | 2019-03-31 | $14.4M | $7.5M | +109.45% |
| Q4 2018 | 2018-12-31 | $11.8M | $6.0M | +103.69% |
| Q3 2018 | 2018-09-30 | $8.9M | $2.7M | +43.12% |
| Q2 2018 | 2018-06-30 | $9.1M | $3.3M | +56.33% |
| Q1 2018 | 2018-03-31 | $6.9M | $1.9M | +38.82% |
| Q4 2017 | 2017-12-31 | $5.8M | $1.1M | +22.14% |
| Q3 2017 | 2017-09-30 | $6.2M | $854,000 | +15.86% |
| Q2 2017 | 2017-06-30 | $5.8M | $1.4M | +32.01% |
| Q1 2017 | 2017-03-31 | $4.9M | $1.4M | +37.63% |
| Q4 2016 | 2016-12-31 | $4.7M | $776,000 | +19.57% |
| Q3 2016 | 2016-09-30 | $5.4M | $2.3M | +72.10% |
| Q2 2016 | 2016-06-30 | $4.4M | $1.7M | +61.55% |
| Q1 2016 | 2016-03-31 | $3.6M | $2.0M | +121.70% |
| Q4 2015 | 2015-12-31 | $4.0M | — | — |
| Q3 2015 | 2015-09-30 | $3.1M | — | — |
| Q2 2015 | 2015-06-30 | $2.7M | — | — |
| Q1 2015 | 2015-03-31 | $1.6M | — | — |
Spyre Therapeutics r&d spending trends
Over the last five fiscal years, Spyre Therapeutics's r&d spending increased from $59.6M to $171.7M, a change of $112.0M. The latest reported quarter, Q2 2026, shows $65.5M.
About the metric
What research and development spending means
Research and development (R&D) spending covers the costs of creating and improving products, services, software, technologies, and processes. Higher R&D spending may support future innovation, but the amount alone does not show whether those investments will generate returns.
Calculation and source
SEC-reported R&D expense
TickerStat standardizes research and development expense reported in company SEC filings, including the software-specific US-GAAP R&D concept when it is the filer’s primary R&D expense line. It is historical company-reported spending, not an estimate or forecast. Fiscal periods can differ from calendar years, so exact period-end dates are included.
Review Spyre Therapeutics source filings ↗