Revenue
2023
2024
2025
Upstream Bio, Inc. (UPB)
Price—Loading quote
Net income
2023
2024
2025
Free cash flow
2023
2024
2025
Total cash / debt
CashTotal debt
2022
2023
2024
2025
Financial statements
| 2025 | 2024 | 2023 | |
|---|---|---|---|
| Revenue | $2.9M | $2.4M | $2.4M |
| Research & development | $136.8M | $63.0M | $31.8M |
| Operating expenses | $163.2M | $80.1M | $42.5M |
| Operating income | −$160.4M | −$77.8M | −$40.1M |
| EBITDAderived | −$160.2M | −$77.7M | −$40.1M |
| Net income | −$143.4M | −$62.8M | −$20.5M |
| Basic EPSper diluted share | -$2.66 | -$5.58 | -$12.95 |
| Diluted EPSper diluted share | -$2.66 | -$5.58 | -$12.95 |
Insider buys & sells
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 16, 2026Form 4 | GRAY MICHAELCFO and COO | SellCommon Stock | 853 | $6.10 | $5.2K | 28.8K |
| Jun 16, 2026Form 4 | Sutherland Everett RandChief Executive Officer | SellCommon Stock | 2.1K | $6.10 | $12.8K | 70.8K |
| Jun 16, 2026Form 4 | Houghton AdamChief Business Officer | SellCommon Stock | 700 | $6.10 | $4.3K | 23.6K |
| Jun 16, 2026Form 4 | Deykin AaronChief Medical Officer | SellCommon Stock | 895 | $6.10 | $5.5K | 33.2K |
| Jun 16, 2026Form 4 | Ambrose AllisonGeneral Counsel | SellCommon Stock | 477 | $6.10 | $2.9K | 16.0K |