Revenue
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $9.89B | $9.68B | $9.84B | $10.17B | $10.98B | $13.44B | $14.38B | $13.45B | $12.27B | $11.45B | $10.76B | $9.70B | $6.93B | $5.52B | $5.05B | $4.72B | $4.38B | $4.10B | $3.17B |
| Gross profit | $7.49B | $7.37B | $7.30B | $7.90B | $8.87B | $11.64B | $12.42B | $11.64B | $10.64B | $9.97B | $9.52B | $8.53B | $6.07B | $4.97B | $4.58B | $4.32B | $4.00B | $3.70B | $2.84B |
| Gross margin | 75.69% | 76.12% | 74.24% | 77.61% | 80.79% | 86.57% | 86.40% | 86.50% | 86.72% | 87.08% | 88.48% | 87.93% | 87.63% | 90.11% | 90.76% | 91.51% | 91.27% | 90.19% | 89.43% |
| Research & development | $1.78B | $1.98B | $2.45B | $2.23B | $2.50B | $3.99B | $2.28B | $2.60B | $2.25B | $1.97B | $2.01B | $1.89B | $1.44B | $1.33B | $1.22B | $1.25B | $1.28B | $1.07B | $925.2M |
| Operating expenses | $8.33B | $7.77B | $8.54B | $6.58B | $8.14B | $8.89B | $7.34B | $7.56B | $6.93B | $6.30B | $5.87B | $5.75B | $3.56B | $3.12B | $3.32B | $3.47B | $3.08B | $2.88B | $2.39B |
| Operating income | $1.56B | $1.91B | $1.30B | $3.59B | $2.84B | $4.55B | $7.04B | $5.89B | $5.35B | $5.15B | $4.89B | $3.97B | $2.52B | $1.86B | $1.72B | $1.25B | $1.30B | $1.21B | $779.8M |
| Operating margin | 15.74% | 19.70% | 13.18% | 35.31% | 25.87% | 33.84% | 48.98% | 43.77% | 43.55% | 45.00% | 45.44% | 40.94% | 36.29% | 33.64% | 34.16% | 26.48% | 29.59% | 29.62% | 24.59% |
| EBITDA | $2.34B | $2.58B | $1.79B | $4.11B | $3.33B | $5.01B | $7.51B | $6.54B | $6.43B | $5.83B | $5.49B | $4.66B | $3.05B | $2.22B | $2.08B | $1.60B | $1.72B | $1.68B | $1.16B |
| EBITDA margin | 23.62% | 26.66% | 18.22% | 40.40% | 30.31% | 37.24% | 52.21% | 48.61% | 52.36% | 50.96% | 51.02% | 48.03% | 43.96% | 40.27% | 41.27% | 34.02% | 39.37% | 40.89% | 36.58% |
| Net income | $1.29B | $1.63B | $1.16B | $3.05B | $1.56B | $4.00B | $5.89B | $4.43B | $2.54B | $3.70B | $3.55B | $2.93B | $1.86B | $1.38B | $1.23B | $1.01B | $970.1M | $783.2M | $638.2M |
| Net profit margin | 13.07% | 16.87% | 11.81% | 29.95% | 14.17% | 29.76% | 40.96% | 32.93% | 20.69% | 32.34% | 32.95% | 30.25% | 26.86% | 25.02% | 24.45% | 21.31% | 22.16% | 19.11% | 20.12% |
| Basic EPSper basic share | $8.83 | $11.21 | $8.02 | $20.96 | $10.44 | $24.86 | $31.47 | $21.63 | $11.94 | $16.96 | $15.38 | $12.42 | $7.86 | $5.80 | $5.09 | $3.98 | $3.37 | $2.67 | $2.02 |
| Diluted EPSper diluted share | $8.79 | $11.18 | $7.97 | $20.87 | $10.40 | $24.80 | $31.42 | $21.58 | $11.92 | $16.93 | $15.34 | $12.37 | $7.81 | $5.76 | $5.04 | $3.94 | $3.35 | $2.65 | $1.99 |
Reported shareholders
Reported holdings Number of shares
| Holder | Shares held |
|---|---|
FMR LLC | 18.22M |
BlackRock, Inc. | 15.99M |
PRIMECAP MANAGEMENT CO/CA/ | 15.15M |
VANGUARD CAPITAL MANAGEMENT LLC | 9.65M |
STATE STREET CORP | 7.34M |
VANGUARD PORTFOLIO MANAGEMENT LLC | 6.6M |
GEODE CAPITAL MANAGEMENT, LLC | 4.45M |
WELLINGTON MANAGEMENT GROUP LLP | 3.12M |
NORGES BANK | 2.58M |
MORGAN STANLEY | 2.41M |
AQR CAPITAL MANAGEMENT LLC | 1.94M |
JPMORGAN CHASE & CO | 1.82M |
Invesco Ltd. | 1.8M |
Amundi | 1.52M |
Legal & General Group Plc | 1.49M |
NORTHERN TRUST CORP | 1.43M |
Boston Partners | 1.26M |
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1.26M |
GOLDMAN SACHS GROUP INC | 1.23M |
DIMENSIONAL FUND ADVISORS LP | 1.15M |
Bars compare reported share counts. A matching total for this share class and reporting period is unavailable, so percentages are not shown.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Feb 12, 2026Form 4 | Murphy NicoleHead of Pharm Ops and Tech | BuyCommon Stock | 3 | $195.04 | $585.12 | 19.6K |
| Feb 9, 2026Form 4 · 10b5-1 | Singhal PriyaHead of Development | SellCommon Stock | 2.7K | $199.83 | $531.5K | 8.0K |
| Feb 2, 2026Form 4 · 10b5-1 | Singhal PriyaHead of Development | SellCommon Stock | 748 | $179.30 | $134.1K | 6.3K |
| Sep 2, 2025Form 4 · 10b5-1 | Singhal PriyaHead of Development | SellCommon Stock | 517 | $133.55 | $69.0K | 5.8K |
| Jul 8, 2025Form 4 · 10b5-1 | Izzar RachidHead of Global Product Strat. | SellCommon Stock | 2.2K | $135.00 | $300.1K | 6.3K |
Biogen ($BIIB) and Eisai received Japanese approval for Leqembi Pen, a subcutaneous formulation of their treatment for early Alzheimer’s disease. The regimen uses two pens totaling 500 milligrams once weekly, offering an alternative to intr ...