Revenue
2010
2012
2013
2014
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 · Dec 31 | 2017 · Jun 30 | 2016 · Dec 31 | 2016 · Jun 30 | 2015 · Dec 31 | 2015 · Jun 30 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $6.4M | $0 | $0 | — | — | — | — | — | — | — | — | — | — | $182,229 | $7,819 | $200,000 | — | $140,000 | — | — | — | — | — | — | — | — | — | — | — |
| Research & development | $3.1M | $3.6M | $8.6M | $23.7M | $22.9M | $14.6M | $26.3M | $20.5M | $16.4M | $733,661 | $9.0M | $2.2M | $5.8M | $4.6M | $3.3M | $2.1M | $2.6M | $3.7M | $2.6M | — | — | — | — | — | — | — | — | — | — | — |
| Operating expenses | $6.4M | $8.8M | $17.3M | $34.4M | $66.0M | $33.5M | $50.6M | $47.6M | $20.4M | — | $9.8M | — | $6.3M | — | — | $4.7M | $5.6M | — | $5.0M | — | — | — | — | — | — | — | — | — | — | — |
| Operating income | −$6.4M | −$2.5M | −$17.3M | −$34.4M | −$66.0M | −$33.5M | −$50.6M | −$47.6M | −$20.4M | −$4.6M | −$9.8M | −$11.2M | −$6.3M | −$18.1M | −$9.1M | −$4.7M | −$5.4M | −$7.9M | −$4.8M | — | — | — | — | — | — | — | — | — | — | — |
| Operating margin | — | −38.81% | — | — | — | — | — | — | — | — | — | — | — | — | −5,019.95% | −59,476.92% | −2,705.76% | — | −3,461.80% | — | — | — | — | — | — | — | — | — | — | — |
| EBITDA | −$6.4M | −$2.4M | −$17.2M | −$34.3M | −$65.9M | −$33.4M | −$50.5M | −$47.3M | −$20.4M | −$4.5M | −$9.8M | −$11.1M | −$6.3M | −$17.9M | −$8.8M | −$4.4M | −$5.2M | −$7.8M | −$4.7M | — | — | — | — | — | — | — | — | — | — | — |
| EBITDA margin | — | −38.26% | — | — | — | — | — | — | — | — | — | — | — | — | −4,828.07% | −55,721.59% | −2,576.75% | — | −3,371.40% | — | — | — | — | — | — | — | — | — | — | — |
| Net income | −$6.0M | −$3.1M | −$17.1M | −$36.1M | −$66.7M | −$34.6M | −$50.9M | −$47.2M | −$21.2M | −$5.8M | −$9.8M | −$8.3M | −$6.4M | −$18.1M | −$9.2M | −$6.1M | −$5.1M | −$7.3M | −$13.4M | −$5.7M | −$4.6M | −$3.3M | −$3.3M | −$3.0M | −$3.7M | −$2.8M | −$3.0M | −$2.0M | −$3.3M | −$1.2M |
| Net profit margin | — | −49.43% | — | — | — | — | — | — | — | — | — | — | — | — | −5,062.44% | −78,303.39% | −2,533.07% | — | −9,559.65% | — | — | — | — | — | — | — | — | — | — | — |
| Basic EPSper basic share | -$5.39 | -$9.24 | -$72.93 | -$183.15 | -$419.65 | -$378.40 | -$589.60 | -$638.00 | -$2,090.00 | -$118.80 | -$1,144.00 | -$184.80 | $734.80 | -$576.40 | -$1,113.20 | -$2,248.40 | -$3,520.00 | -$6,160.00 | -$29,480.00 | — | — | — | — | — | — | — | — | — | — | — |
| Diluted EPSper diluted share | -$5.39 | -$9.24 | -$72.93 | -$183.15 | -$419.65 | -$378.40 | -$589.60 | -$638.00 | -$2,090.00 | -$118.80 | -$1,144.00 | -$184.80 | $734.80 | -$576.40 | -$1,113.20 | -$2,248.40 | -$3,520.00 | -$6,160.00 | -$29,480.00 | — | — | — | — | — | — | — | — | — | — | — |
Eloxx Pharmaceuticals ($ELOX) dosed the first two patients in its Phase 2b EXACT study of exaluren for Alport syndrome caused by nonsense mutations. The trial plans to enroll 24 patients with relevant mutations in the COL4A3, COL4A4 or COL4 ...