Alnylam Pharmaceuticals annual net profit margin
2008
2009
2010
2016
2017
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2021
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2025
Alnylam Pharmaceuticals Net Profit Margin Growth & History (ALNY)
Alnylam Pharmaceuticals's net profit margin was 8.45% for fiscal 2025.
View full Alnylam Pharmaceuticals company overviewAlnylam Pharmaceuticals annual net profit margin history
| Fiscal year | Period ended | Net profit margin | Change (percentage points) |
|---|---|---|---|
| 2025 | 2025-12-31 | 8.45% | +20.82 pp |
| 2024 | 2024-12-31 | −12.37% | +11.71 pp |
| 2023 | 2023-12-31 | −24.08% | +84.96 pp |
| 2022 | 2022-12-31 | −109.04% | −8.02 pp |
| 2021 | 2021-12-31 | −101.01% | +73.13 pp |
| 2020 | 2020-12-31 | −174.15% | +229.09 pp |
| 2019 | 2019-12-31 | −403.24% | +613.34 pp |
| 2018 | 2018-12-31 | −1,016.58% | −470.63 pp |
| 2017 | 2017-12-31 | −545.95% | +323.68 pp |
| 2016 | 2016-12-31 | −869.63% | — |
| 2010 | 2010-12-31 | −43.50% | +3.84 pp |
| 2009 | 2009-12-31 | −47.34% | −20.04 pp |
| 2008 | 2008-12-31 | −27.30% | — |
Alnylam Pharmaceuticals quarterly net profit margin
Q2.09
Q3.09
Q1.10
Q2.10
Q3.10
Q4.10
Q1.11
Q1.17
Q2.17
Q3.17
Q4.17
Q1.18
Q2.18
Q3.18
Q4.18
Q1.19
Q2.19
Q3.19
Q4.19
Q1.20
Q2.20
Q3.20
Q4.20
Q1.21
Q2.21
Q3.21
Q4.21
Q1.22
Q2.22
Q3.22
Q4.22
Q1.23
Q2.23
Q3.23
Q4.23
Q1.24
Q2.24
Q3.24
Q4.24
Q1.25
Q2.25
Q3.25
Q4.25
Q1.26
Q2.26
| Fiscal quarter | Period ended | Net profit margin | Change (percentage points) |
|---|---|---|---|
| Q2 2026 | 2026-06-30 | 12.74% | +22.08 pp |
| Q1 2026 | 2026-03-31 | 17.65% | +20.72 pp |
| Q4 2025 | 2025-12-31 | 13.96% | +28.08 pp |
| Q3 2025 | 2025-09-30 | 20.10% | +42.38 pp |
| Q2 2025 | 2025-06-30 | −9.34% | −6.78 pp |
| Q1 2025 | 2025-03-31 | −3.07% | +10.27 pp |
| Q4 2024 | 2024-12-31 | −14.12% | +17.23 pp |
| Q3 2024 | 2024-09-30 | −22.27% | −41.96 pp |
| Q2 2024 | 2024-06-30 | −2.56% | +84.04 pp |
| Q1 2024 | 2024-03-31 | −13.34% | +41.19 pp |
| Q4 2023 | 2023-12-31 | −31.35% | +30.58 pp |
| Q3 2023 | 2023-09-30 | 19.69% | +173.27 pp |
| Q2 2023 | 2023-06-30 | −86.59% | +36.79 pp |
| Q1 2023 | 2023-03-31 | −54.53% | +58.17 pp |
| Q4 2022 | 2022-12-31 | −61.93% | +38.04 pp |
| Q3 2022 | 2022-09-30 | −153.58% | −44.58 pp |
| Q2 2022 | 2022-06-30 | −123.39% | −37.44 pp |
| Q1 2022 | 2022-03-31 | −112.70% | +0.10 pp |
| Q4 2021 | 2021-12-31 | −99.97% | +48.93 pp |
| Q3 2021 | 2021-09-30 | −109.00% | +92.26 pp |
| Q2 2021 | 2021-06-30 | −85.95% | +86.45 pp |
| Q1 2021 | 2021-03-31 | −112.80% | +70.38 pp |
| Q4 2020 | 2020-12-31 | −148.90% | +236.40 pp |
| Q3 2020 | 2020-09-30 | −201.26% | +96.39 pp |
| Q2 2020 | 2020-06-30 | −172.40% | +318.46 pp |
| Q1 2020 | 2020-03-31 | −183.18% | +363.21 pp |
| Q4 2019 | 2019-12-31 | −385.30% | +619.98 pp |
| Q3 2019 | 2019-09-30 | −297.65% | +11557.45 pp |
| Q2 2019 | 2019-06-30 | −490.86% | +56.04 pp |
| Q1 2019 | 2019-03-31 | −546.39% | +98.45 pp |
| Q4 2018 | 2018-12-31 | −1,005.28% | −630.25 pp |
| Q3 2018 | 2018-09-30 | −11,855.10% | −11136.00 pp |
| Q2 2018 | 2018-06-30 | −546.90% | +196.39 pp |
| Q1 2018 | 2018-03-31 | −644.84% | −78.97 pp |
| Q4 2017 | 2017-12-31 | −375.03% | — |
| Q3 2017 | 2017-09-30 | −719.10% | — |
| Q2 2017 | 2017-06-30 | −743.28% | — |
| Q1 2017 | 2017-03-31 | −565.88% | — |
| Q1 2011 | 2011-03-31 | −77.93% | −27.76 pp |
| Q4 2010 | 2010-12-31 | −32.70% | — |
| Q3 2010 | 2010-09-30 | −34.81% | +3.17 pp |
| Q2 2010 | 2010-06-30 | −54.97% | +37.31 pp |
| Q1 2010 | 2010-03-31 | −50.17% | — |
| Q3 2009 | 2009-09-30 | −37.97% | — |
| Q2 2009 | 2009-06-30 | −92.28% | — |
Alnylam Pharmaceuticals net profit margin trends
Over the last five fiscal years, Alnylam Pharmaceuticals's net profit margin increased from −174.15% to 8.45%, a change of +182.59 percentage points. The latest reported quarter, Q2 2026, shows 12.74%.
About the metric
What net profit margin means
Net profit margin measures the percentage of revenue remaining as net income after operating costs, interest, taxes, and other expenses. It shows how much bottom-line profit or loss a company generates from each dollar of revenue.
Calculation and source
How net profit margin is calculated
TickerStat calculates net profit margin as SEC-reported net income divided by SEC-reported revenue for the same fiscal period. Changes are shown in percentage points. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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