Ionis Pharmaceuticals annual debt-to-equity ratio
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2025
Ionis Pharmaceuticals Debt-to-Equity Ratio Growth & History (IONS)
Ionis Pharmaceuticals's debt-to-equity ratio was 4.15 for fiscal 2025.
View full Ionis Pharmaceuticals company overviewIonis Pharmaceuticals annual debt-to-equity ratio history
| Fiscal year | Period ended | Debt-to-equity ratio | Change | Growth |
|---|---|---|---|---|
| 2025 | 2025-12-31 | 4.15 | 1.82 | +77.98% |
| 2024 | 2024-12-31 | 2.33 | −1.34 | −36.44% |
| 2023 | 2023-12-31 | 3.67 | 1.30 | +54.47% |
| 2022 | 2022-12-31 | 2.38 | 2.35 | +8218.05% |
| 2021 | 2021-12-31 | 0.03 | −1.12 | −97.52% |
| 2020 | 2020-12-31 | 1.15 | 0.61 | +110.74% |
| 2019 | 2019-12-31 | 0.55 | −0.01 | −1.48% |
| 2018 | 2018-12-31 | 0.56 | −1.35 | −70.82% |
| 2017 | 2017-12-31 | 1.90 | −3.14 | −62.24% |
| 2016 | 2016-12-31 | 5.04 | 5.04 | +196357.58% |
| 2015 | 2015-12-31 | 0.00 | −0.01 | −77.06% |
| 2014 | 2014-12-31 | 0.01 | −0.40 | −97.27% |
| 2013 | 2013-12-31 | 0.41 | −0.41 | −49.79% |
| 2012 | 2012-12-31 | 0.81 | −0.03 | −4.08% |
| 2011 | 2011-12-31 | 0.85 | 0.24 | +39.59% |
| 2010 | 2010-12-31 | 0.61 | 0.57 | +1446.11% |
| 2009 | 2009-12-31 | 0.04 | — | — |
Ionis Pharmaceuticals quarterly debt-to-equity ratio
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Q2.26
| Fiscal quarter | Period ended | Debt-to-equity ratio | Change | YoY change |
|---|---|---|---|---|
| Q2 2026 | 2026-06-30 | 0.60 | −1.65 | −73.45% |
| Q1 2026 | 2026-03-31 | 0.53 | 0.19 | +57.44% |
| Q4 2025 | 2025-12-31 | 4.15 | 1.82 | +77.98% |
| Q3 2025 | 2025-09-30 | 0.43 | 0.17 | +67.24% |
| Q2 2025 | 2025-06-30 | 2.25 | 1.62 | +256.13% |
| Q1 2025 | 2025-03-31 | 0.34 | −0.23 | −41.10% |
| Q4 2024 | 2024-12-31 | 2.33 | −1.34 | −36.44% |
| Q3 2024 | 2024-09-30 | 0.25 | −0.29 | −53.67% |
| Q2 2024 | 2024-06-30 | 0.63 | 0.22 | +54.46% |
| Q1 2024 | 2024-03-31 | 0.57 | 0.21 | +56.38% |
| Q4 2023 | 2023-12-31 | 3.67 | 1.30 | +54.47% |
| Q3 2023 | 2023-09-30 | 0.55 | — | — |
| Q2 2023 | 2023-06-30 | 0.41 | — | — |
| Q1 2023 | 2023-03-31 | 0.36 | — | — |
| Q4 2022 | 2022-12-31 | 2.38 | 2.35 | +8218.05% |
| Q4 2021 | 2021-12-31 | 0.03 | −1.12 | −97.52% |
| Q4 2020 | 2020-12-31 | 1.15 | 0.61 | +110.74% |
| Q4 2019 | 2019-12-31 | 0.55 | −0.01 | −1.48% |
| Q3 2019 | 2019-09-30 | 0.46 | −0.33 | −41.41% |
| Q2 2019 | 2019-06-30 | 0.49 | −0.30 | −38.32% |
| Q1 2019 | 2019-03-31 | 0.51 | −1.29 | −71.90% |
| Q4 2018 | 2018-12-31 | 0.56 | −1.35 | −70.82% |
| Q3 2018 | 2018-09-30 | 0.79 | −0.92 | −53.81% |
| Q2 2018 | 2018-06-30 | 0.79 | −1.61 | −67.01% |
| Q1 2018 | 2018-03-31 | 1.80 | −0.72 | −28.67% |
| Q4 2017 | 2017-12-31 | 1.90 | −3.14 | −62.24% |
| Q3 2017 | 2017-09-30 | 1.70 | 1.70 | +485470.77% |
| Q2 2017 | 2017-06-30 | 2.40 | 2.32 | +2995.75% |
| Q1 2017 | 2017-03-31 | 2.52 | 2.46 | +4414.60% |
| Q4 2016 | 2016-12-31 | 5.04 | 5.04 | +196357.58% |
| Q3 2016 | 2016-09-30 | 0.00 | −0.00 | −88.86% |
| Q2 2016 | 2016-06-30 | 0.08 | 0.07 | +1797.56% |
| Q1 2016 | 2016-03-31 | 0.06 | 0.05 | +647.98% |
| Q4 2015 | 2015-12-31 | 0.00 | −0.01 | −77.06% |
| Q3 2015 | 2015-09-30 | 0.00 | −0.46 | −99.32% |
| Q2 2015 | 2015-06-30 | 0.00 | −0.43 | −99.05% |
| Q1 2015 | 2015-03-31 | 0.01 | −0.41 | −98.21% |
| Q4 2014 | 2014-12-31 | 0.01 | −0.40 | −97.27% |
| Q3 2014 | 2014-09-30 | 0.46 | 0.08 | +20.80% |
| Q2 2014 | 2014-06-30 | 0.43 | 0.05 | +13.61% |
| Q1 2014 | 2014-03-31 | 0.42 | −0.33 | −44.00% |
| Q4 2013 | 2013-12-31 | 0.41 | −0.41 | −49.79% |
| Q3 2013 | 2013-09-30 | 0.38 | −0.49 | −55.96% |
| Q2 2013 | 2013-06-30 | 0.38 | 0.34 | +1000.37% |
| Q1 2013 | 2013-03-31 | 0.75 | 0.73 | +3727.64% |
| Q4 2012 | 2012-12-31 | 0.81 | −0.03 | −4.08% |
| Q3 2012 | 2012-09-30 | 0.87 | 0.84 | +3330.02% |
| Q2 2012 | 2012-06-30 | 0.03 | 0.01 | +33.70% |
| Q1 2012 | 2012-03-31 | 0.02 | −0.00 | −10.11% |
| Q4 2011 | 2011-12-31 | 0.85 | 0.24 | +39.59% |
| Q3 2011 | 2011-09-30 | 0.03 | 0.01 | +49.05% |
| Q2 2011 | 2011-06-30 | 0.03 | 0.00 | +20.16% |
| Q1 2011 | 2011-03-31 | 0.02 | — | — |
| Q4 2010 | 2010-12-31 | 0.61 | 0.57 | +1446.11% |
| Q3 2010 | 2010-09-30 | 0.02 | — | — |
| Q2 2010 | 2010-06-30 | 0.02 | — | — |
| Q4 2009 | 2009-12-31 | 0.04 | — | — |
Ionis Pharmaceuticals debt-to-equity ratio trends
Over the last five fiscal years, Ionis Pharmaceuticals's debt-to-equity ratio increased from 1.15 to 4.15, a change of 3.00. The latest reported quarter, Q2 2026, shows 0.60.
About the metric
What the debt-to-equity ratio means
The debt-to-equity ratio compares interest-bearing debt with shareholders’ equity. It helps show how much debt financing a company uses relative to its accounting equity, but useful comparison levels vary by industry.
Calculation and source
How debt-to-equity is calculated
TickerStat calculates debt-to-equity as total interest-bearing debt divided by SEC-reported shareholders’ equity for the same balance-sheet date. Total liabilities are not treated as debt, and periods with non-positive equity are omitted. Fiscal periods can differ from calendar years, so exact period-end dates are included.
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