Revenue
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $655.4M | $605.2M | $509.3M | $537.8M | $535.0M | $494.4M | $351.3M | $248.1M | $177.0M | $82.9M | $33.1M | $15.5M | $10.4M |
| Gross profit | $488.5M | $468.0M | $381.1M | $423.0M | $420.2M | $387.9M | $262.7M | $168.0M | $121.4M | $36.6M | $12.5M | $5.5M | $3.3M |
| Gross margin | 74.54% | 77.33% | 74.81% | 78.64% | 78.53% | 78.46% | 74.78% | 67.73% | 68.59% | 44.16% | 37.71% | 35.21% | 32.30% |
| Research & development | $224.5M | $209.6M | $223.1M | $206.1M | $201.3M | $132.0M | $79.0M | $50.6M | $38.1M | $41.5M | $43.7M | $40.4M | $34.8M |
| Operating expenses | $642.3M | $638.5M | $613.9M | $512.5M | $464.5M | $357.5M | $263.6M | $201.7M | $160.7M | $151.9M | $116.5M | $85.6M | $67.8M |
| Operating income | −$153.8M | −$170.5M | −$232.9M | −$89.5M | −$44.3M | $30.4M | −$914,000 | −$33.7M | −$39.3M | −$115.3M | −$104.0M | −$80.2M | −$64.5M |
| Operating margin | −23.47% | −28.17% | −45.72% | −16.64% | −8.29% | 6.15% | −0.26% | −13.57% | −22.22% | −139.12% | −314.31% | −517.47% | −622.25% |
| EBITDA | −$139.2M | −$159.3M | −$221.9M | −$78.9M | −$34.1M | $39.6M | $7.5M | −$24.7M | −$31.7M | −$109.7M | −$100.8M | −$78.2M | −$63.2M |
| EBITDA margin | −21.23% | −26.31% | −43.57% | −14.67% | −6.37% | 8.00% | 2.15% | −9.94% | −17.88% | −132.31% | −304.78% | −504.80% | −610.51% |
| Net income | −$136.2M | −$168.6M | −$207.0M | −$92.5M | −$58.4M | $19.8M | −$7.2M | −$63.6M | −$61.7M | −$131.8M | −$111.6M | −$80.7M | −$77.4M |
| Net profit margin | −20.79% | −27.86% | −40.65% | −17.20% | −10.91% | 4.01% | −2.06% | −25.62% | −34.83% | −159.06% | −337.24% | −520.87% | −746.89% |
| Basic EPSper basic share | -$1.22 | -$1.56 | -$1.95 | -$0.88 | -$0.56 | $0.20 | -$0.07 | -$0.69 | -$0.70 | -$1.54 | -$3.67 | -$6.46 | -$6.73 |
| Diluted EPSper diluted share | -$1.22 | -$1.56 | -$1.95 | -$0.88 | -$0.56 | $0.18 | -$0.07 | -$0.69 | -$0.70 | -$1.54 | -$3.67 | -$6.46 | -$6.73 |
Reported shareholders
| Holder | % owned |
|---|---|
FMR LLC | 14.92%17.37M shares |
BlackRock, Inc. | 11.52%13.41M shares |
Soleus Capital Management, L.P. | 8.51%9.91M shares |
VANGUARD PORTFOLIO MANAGEMENT LLC | 5.39%6.27M shares |
VANGUARD CAPITAL MANAGEMENT LLC | 4.21%4.9M shares |
MORGAN STANLEY | 3.88%4.52M shares |
STATE STREET CORP | 2.46%2.87M shares |
GEODE CAPITAL MANAGEMENT, LLC | 2.40%2.8M shares |
WELLS FARGO & COMPANY/MN | 2.17%2.53M shares |
Quantinno Capital Management LP | 1.91%2.22M shares |
RENAISSANCE TECHNOLOGIES LLC | 1.68%1.95M shares |
JPMORGAN CHASE & CO | 1.44%1.67M shares |
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1.19%1.39M shares |
Palo Alto Investors LP | 1.10%1.28M shares |
Nuveen, LLC | 1.06%1.23M shares |
JACOBS LEVY EQUITY MANAGEMENT, INC | 1.00%1.16M shares |
Empowered Funds, LLC | 0.99%1.15M shares |
AQR CAPITAL MANAGEMENT LLC | 0.95%1.1M shares |
DIMENSIONAL FUND ADVISORS LP | 0.94%1.09M shares |
D. E. Shaw & Co., Inc. | 0.88%1.02M shares |
Percentages use 116.44M shares of this listed class outstanding on Jun 30, 2026.
Gray completes the 100% scale. Reported positions may overlap; holders have different reporting dates.
| Transaction | Insider | Type | Shares | Price | Value | Owned after |
|---|---|---|---|---|---|---|
| Jun 4, 2026Form 4 | Leonard Frank XChief Executive Officer | SellOrdinary Shares | 34.3K | $17.93 | $614.5K | 459.5K |
| Jun 2, 2026Form 4 | Stafford KristinDirector | SellOrdinary Shares | 2.9K | $15.77 | $46.4K | 11.3K |
| Jun 2, 2026Form 4 | Ocean Allyson JDirector | SellOrdinary Shares | 2.9K | $15.77 | $46.4K | 11.3K |
| Jun 2, 2026Form 4 | Scannell Timothy JDirector | SellOrdinary Shares | 2.9K | $15.77 | $46.4K | 14.3K |
| Jun 2, 2026Form 4 | VERNON W ANTHONYDirector | SellOrdinary Shares | 2.9K | $15.77 | $46.4K | 197.7K |